This site is intended for healthcare professionals. If you are a patient or caregiver, please contact your physician to discuss clinical trial eligibility.

Focused on the research and development of highly selective medicines for pediatric and adult patients with genomically defined cancers

At Loxo Oncology, we are focused on developing medicines that selectively inhibit a single cancer-driving molecular target. Our programs are designed to leverage recent advances in genomic testing to identify the patients most likely to benefit.

Explore our pipeline and clinical development programs to determine their ability to inhibit cancer-driving molecular targets in solid tumors and hematologic malignancies.

TRK Trials logo

Exploring new paths to tumor-agnostic selective TRK inhibition

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RET Trials logo

Orchestrating a new investigational approach to researching RET-altered cancers

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BTK Trials logo

Researching a new strategy to address resistance and intolerance to covalent BTK inhibitors

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